Genotype-to-phenotype maps and the related fitness landscapes that include epistatic interactions are difficult to measure because of their high dimensional structure.Here we construct such a map using the recently collected corpora of high-throughput sequence data from the 75 base pairs long mutagenized E.coli lac promoter region, where each seque
By analyzing the Byzantine sources, the author presents a thorough picture of Nail Polish the Arsenite faction and the internal schism occurred in the Byzantine society as a result of their actions.Beside their uncompromising position towards emperor Michael VIII Palaiologos, always supported with spiritual arguments, the Arsenites also had concret
Human as mysterious creatures cannot if only be approached by a scientific discipline, they must be understood in an interdisciplinary manner.In writing this journal explaining the possibility of Islamic education has a transdisciplinary meaning to eliminate the separation between general science and the science of religion and all the knowledge Ga
In this retrospective study to determine the optimal method of evaluating static weight-bearing distribution to assess response to treatment in dogs with osteoarthritis using a weight distribution platform, data from the Clinica Veterinária de Cães (Portuguese Republican National Guard) clinical records were extracted.At baseline and at 15 days p
Pipelines are widely used for the transportation of hydrocarbon fluids over millions of miles all over the world.The structures of the pipelines are designed to withstand several environmental loading conditions to ensure safe and reliable distribution from point of production to the shore or distribution depot.However, leaks in pipeline networks a